Iraqi Journal of Veterinary Sciences

Abstract

The aim of this study was to evaluate the humeral immune response induced by administration of smooth strain of B. melitensis Rev. 1 vaccine (1-2× 109 viable organism per dose) given by subcutaneous and intraocular routes in goats. Rose Bengal test was done to ensure the absence of Brucella infection in experimental animals and the 2- ME agglutination test was used to evaluate the antibody titers. The results showed that subcutaneous group showed positive results in 80% of animals whereas 38.5% of intraocular group showed positive results.