Abstract
Moxidectin is a second generation semi-synthetic Macrocyclic Lactone of the Milbemycins family, which have a broad spectrum of activity against external and internal parasite including Oestrus ovis and hypodermatosis. A trial was conducted to identify the efficacy of moxidectin against the natural infection of cattle with larvae of screw worm fly Chrysomya bezziana. A dose of 0.2 mg/ kg b.wt. (1 ml /50kg b. wt.) S.C . which was found to be very effective for more than 40 days? The trial shows the effect of Moxidectin is over that of Ivermectin in re-infection of the animal. No side effects & no abnormal behaviors, was noticed on the animals treated with Moxidectin during the trial.
)
