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Official Journal of the College of Veterinary Medicine, University of Mosul
Abstract
In this study the ED50 of tramadol was evaluated and it was found to be equal to (0.85 mg/kg). The analgesic effect of tramadol (1 mg/kg) by subcutaneous route was investigated in chicks by using electrical stimulator. The drug induce a safe and effective analgesia within 30 minute and lasted for 90 minute after injection. Tramadol also produce sedative effect within 40 minute after administration and last up to 80 minute, presented by dropping of the head and wings, ataxia, lying but able to rise and recumbency then loss of consciousness. The administration of tramadol produce a dose- depended antinociceptive effect with 10 mg/kg as maximum effective dose. This study concluded that tramadol have a good analgesic activity in chicks.
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