Abstract
Three hundred skin tissue biopsies from ear pinna of local breed cattle during 2008–2009 (from July 2008 to May 2009) to detect bovine viral diarrhea virus antigens in persistently infected calves and cows, by using indirect immunohistochemistry test (IHC). Out of 300 samples examined 25.3 % were positive for IHC test (Draa province 38.6%, Homs 21.3%, Hama 25.3%, and Aleppo 16%). Infection was observed in 22%, 41%, 13% of calves less than 6 months, calves between 6-12 months and cows, respectively.