Abstract

The study was carried out to detect the effect of the oil extracted from Nigella sativa seeds in ameliorating adverse effects of cadmium related to hematology and fertility parameters in adult male rats. Eighteen male albino rats were divided into 3 group (6 animals/group), the first group considered as control, the second was treated with cadmium chloride (25 mg/L) in drinking water while the third one was treated with cadmium chloride (25 mg/L) in drinking water together with extracted oil of Nigella sativa (2.5 g/kg) through oral gavaging for 30 days. Blood samples and genital organs were obtained at the end of experiment. Results showed the efficient effect of extracted oil in the up regulation of RBCs, WBCs, Hb and PCV significantly which they revealed a decline caused by the treatment with cadmium alone when compared with control group. Genital organs weights ratio and accessory glands were also up regulated by the treatment with extract oil at the same time of that observed in hematology, body weight, total sperm count, live sperms while abnormal sperms declined significantly; values elevated too to parallel that’s of control. In conclusion, treatment with the extracted oil of Nigella sativa is effective in limiting the negative effects related to hematology and fertility resulted from the treatment with cadmium chloride in adult male rats.