This study was designed to determine the level of immunity and efficacy of body weight in different age in broilers by live attenuated with adjuvant and killed vaccines (LaSota strain). In this study used (8) groups of broiler, first five groups vaccinated with different vaccination program, another (3) groups as control. Results reveal that no significant increase in mean body weight at 18-28 days in all groups, but significant increase at 28-35 days age in groups (1,4) on groups (6,8) at (P<0.05). ELISA shows presence of not specific antibody in the sera at vaccinated groups in 18 days age, where presence of specific antibody at group 2 compare with group 3 in 28 days age, also specific antibody at group 3 compared with group4 in 35 days age at (P<0.05). HI shows presence of not specific antibody in the sera at vaccinated groups in 18 days age, where presence of specific antibody at group 4 compared with groups 1,2,3 in 28 days age, but where is 35 days age which presence of specific antibody at group 2 compared with group (1 and 5) at (P<0.05). The result of Maternal Antiboday revealed in ELISA & HI which decrease of specific antibody in broiler chicks at 8 days age. The result of Phagocytic index revealed occurrence of specific phagocyte at 35 days age in group 5 compared with group (7 and 8) and also presence specific phagocyte in group (2,3 and 4) compared with group 6 at (P<0.05).