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The histological and histochemical changes in the kidney of rabbit induced by diazinon

    Authors

    • S. A. Sadiq
    • M. T. Jarjees

    Department of Anatomy, College of Medicine, University of Mosul, Mosul, Iraq

,

Document Type : Research Paper

10.33899/ijvs.2019.153868
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Abstract

Diazinon (DZN) is a commonly used Organophosphorus (OP) pesticide to control a variety of insects in agriculture and in the environment. The aim of this project is to study the effects of organophospherous pesticide (Diazinon) on histological and histochemical of kidney in male rabbit. The present study is based upon observations made on 24 male Baladi rabbits, which was divided into: 3 groups: Eight animals each, the whole body of the rabbit was dipped in 10 liters of the diazinon solution, while sparing the head for 10 seconds. Group one (control group) was dipped in water only. Animals of Group 2; were dipped in diazinon solution dipped every 2 days for 4 weeks, and Group 3 were dipped in diazinon solution every 7days for two months. Decreased in body weight was noticed in group 2 and group 3 may be due to increases in the exposed doses and increased accumulation of DZN in the blood of the exposure animals. Histological changes in group 2 and 3 are similar, renal tubules were severely damaged with cytoplasmic vacuolation and atrophy of some glomeruli. Blood capillaries in between the degenerated tubules were congested; the urine spaces are widening, and fibrosis inters tubules in group 3 only. Exposure of animals to diazinon caused extensive changes in histopathologicaly as well as histochemicaly in the kidney of group 2 and group 3. But very marked changes in group 3.

Keywords

  • Diazinon
  • kidney
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Iraqi Journal of Veterinary Sciences
Volume 32, Issue 2
December 2018
Page 303-308
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  • PDF 1000.69 K
History
  • Received: 28 February 2018
  • Revised: 28 January 2019
  • Accepted: 22 April 2018
  • Published: 28 January 2019
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  • Article View: 933
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APA

Sadiq, S., & Jarjees, M. (2019). The histological and histochemical changes in the kidney of rabbit induced by diazinon. Iraqi Journal of Veterinary Sciences, 32(2), 303-308. doi: 10.33899/ijvs.2019.153868

MLA

S. A. Sadiq; M. T. Jarjees. "The histological and histochemical changes in the kidney of rabbit induced by diazinon". Iraqi Journal of Veterinary Sciences, 32, 2, 2019, 303-308. doi: 10.33899/ijvs.2019.153868

HARVARD

Sadiq, S., Jarjees, M. (2019). 'The histological and histochemical changes in the kidney of rabbit induced by diazinon', Iraqi Journal of Veterinary Sciences, 32(2), pp. 303-308. doi: 10.33899/ijvs.2019.153868

VANCOUVER

Sadiq, S., Jarjees, M. The histological and histochemical changes in the kidney of rabbit induced by diazinon. Iraqi Journal of Veterinary Sciences, 2019; 32(2): 303-308. doi: 10.33899/ijvs.2019.153868

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