College of Veterinary Medicine / University of Mosul
  • Register
  • Login
  • العربیة

Iraqi Journal of Veterinary Sciences

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 32, Issue 1
  3. Authors

Current Issue

By Issue

By Subject

Keyword Index

Author Index

Indexing Databases XML

About Journal

Aims and Scope

Editorial Board

Editorial Staff

Facts and Figures

Publication Ethics

Indexing and Abstracting

Related Links

FAQ

Peer Review Process

News

Potency Syzygium cumini L as adjuvant therapy on mice model malaria

    L. Maslachah R. Sugihartuti

Iraqi Journal of Veterinary Sciences, 2018, Volume 32, Issue 1, Pages 73-80
10.33899/ijvs.2018.153801

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

The objective of the study was to prove the potential extract of Syzygium cumini L leaf and stem bark as an adjuvant to malaria modelling mice. Antimalarial effects were assessed by the percentage of parasitemia, growth inhibition, 50% dose level (ED50), Parasite Clearance Time (PCT), Recrudescence Time (RT) of Plasmodium berghei. Male albino Swiss mice infected with 1x105 P. berghei parasite in 0.2 ml intraperitoneally. Treatment with chloroquine 25 mg/kg body weight, chloroquine combination 25 mg/kg body weight with leaf and stem bark extract of Syzygium cumini L dose 600 mg / kg body weight for 4 days and 24 hours after infection, and then its activity as antimalarial and adjuvant therapy were observed. The results showed that the extract of Syzygium cumini L leaf combined with chloroquine gives highly significant result in inhibiting the growth of parasites than the chloroquine alone and the extract of Syzygium cumini L leaf combined with chloroquine gives the Parasite Clearance Time faster and Recrudescence Time (RT) longer than the other treatment.
Keywords:
    Syzygium Plasmodium adjuvant
Main Subjects:
  • Animal Immunology
  • PDF
  • XML
(2018). Potency Syzygium cumini L as adjuvant therapy on mice model malaria. Iraqi Journal of Veterinary Sciences, 32(1), 73-80. doi: 10.33899/ijvs.2018.153801
L. Maslachah; R. Sugihartuti. "Potency Syzygium cumini L as adjuvant therapy on mice model malaria". Iraqi Journal of Veterinary Sciences, 32, 1, 2018, 73-80. doi: 10.33899/ijvs.2018.153801
(2018). 'Potency Syzygium cumini L as adjuvant therapy on mice model malaria', Iraqi Journal of Veterinary Sciences, 32(1), pp. 73-80. doi: 10.33899/ijvs.2018.153801
Potency Syzygium cumini L as adjuvant therapy on mice model malaria. Iraqi Journal of Veterinary Sciences, 2018; 32(1): 73-80. doi: 10.33899/ijvs.2018.153801
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 684
  • PDF Download: 407
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

© 2023, College of Veterinary Medicine, University of Mosul

 
Powered by eJournalPlus