TY - JOUR ID - 167612 TI - Effect of aqueous rosemary extract on some sexual hormones in male rats with high thyroxine level JO - Iraqi Journal of Veterinary Sciences JA - IJVS LA - en SN - 1607-3894 AU - Hamza, Fouad Z. AU - Al-Sharafi, Nabeel M. AU - Kasim, Sumayah F. AD - College of Veterinary Medicine, University of Kufa, Kufa, Iraq AD - College of Health and Medical Technology, Middle Technical University, Baghdad, Iraq Y1 - 2021 PY - 2021 VL - 35 IS - 2 SP - 369 EP - 373 KW - Testosterone KW - FSH KW - LH KW - Levothyroxine KW - Herbs DO - 10.33899/ijvs.2020.126872.1404 N2 - The main purpose of this research is to evaluate the high level of thyroxine affects on each of the luteinizing hormone (LH), testosterone, follicle-stimulating hormone (FSH) of rats and to estimate the potential effect of the administration of aqueous rosemary extract and propylthiouracil against testicular toxicity induced by levothyroxine in male rats. Negative control group rats were treated with distilled water. Three groups of male rats were treated subcutaneously with 0.5 mg/kg levothyroxine for 12 days: Since day 13th to the 24th day of the experiment first group was regarded as a positive control group that received distilled water, the second group was given propylthiouracil at a dose level of 10 mg/kg b.wt, and the third was given aqueous extracts of rosemary 10 mg/kg b.wt. The results revealed that treatment with aqueous extract of rosemary lead to a significant decrease in the levels of serum testosterone while a highly significant decrease in testosterone, FSH, and LH levels in serum revealed after treatment with propylthiouracil. Thus, it can be concluded that the effect of propylthiouracil and rosemary aqueous extract resulted in dialectical hormonal results in which the favor was to propylthiouracil. UR - https://www.vetmedmosul.com/article_167612.html L1 - https://www.vetmedmosul.com/article_167612_05ed8c3ab8c13af88b989c1e82796af4.pdf ER -