Keywords : Cornea

Protective effect of quercetin against corneal toxicities induced by cisplatin in male mice

Semaa A. Baker; Mahdi A. Ali Abdullah; Ali A. Abed

Iraqi Journal of Veterinary Sciences, 2022, Volume 36, Issue 2, Pages 321-326
DOI: 10.33899/ijvs.2021.130145.1741

The Aim of study was conducted to evaluate the potential protective role of quercetin against the corneal toxicity which caused by administration of cisplatin in male mice. Thirty-six adult male albino mice were divided into three equal groups; Group I control, Group II cisplatin mice injected as single dose I.P of cisplatin 10 mg/kg, and Group III mice received Q 75 mg/ kg with cisplatin 10 mg/ kg. The treatment continues for eight days then the tissues were collected for histopathological study. The histopathological changes in the cornea of eye were demonstrated in groups of mice received cisplatin. The changes represented by damages of superficial epithelial layer, vacuolar degeneration, hyperplasia, separation of stromal layer and sever damage of the stromal hemorrhage, and perforation of sclera, edema and inflammatory cells infiltration as well as separation of descement membrane from stroma layer. While these changes were diminished when the mice are treated with Q in the combination of cisplatin in comparison to treated cisplatin alone mice. Cisplatin induced structural and histopathological changes in the cornea of adult albino rat that could be ameliorated by concomitant treatment with quercetin.

Effect of mobile frequencies exposure on histology of retina and cornea in pregnant albino mice

Rawah N. Alshammary; Zeena D. Mohammed Zaki; Ammar G. Al-Haaik

Iraqi Journal of Veterinary Sciences, 2022, Volume 36, Issue 1, Pages 245-249
DOI: 10.33899/ijvs.2021.129839.1701

In the current study, the potential effects of the Nokia mobile device were studied with frequency 900-1800 Mhz on the eyes of pregnant and non-pregnant female Swiss mice. The mice were divided into three groups: The first group is a control group consisting of five mice, the second group consists of 10 mice and the third group consists of 10 pregnant mice. Female mice of the second and third groups were exposed for a 3 hour / day and for a 30 days to a mobile device. After the end of 30 days, mice were euthanized and tissue samples were taken from the eyes of pregnant and non-pregnant mice. Microscopic examination showed, that there are significant effects on the cornea and retina of the eye, especially in pregnant females, which supports the current studies conducted on the effect of mobile phones on the eyes represented by vascularization where some sections showed newly formed blood vessels in stroma layer just beneath bowman's membrane and retina degeneration. This study concluded that the exposure to the mobile radiation led to serious histological changes in the tissues of eye which may lead to blindness.

Anatomical and histological structure of the cornea in Sparrow hawk Accipiter nisus

Hamid H. Hamid; Ameer M. Taha

Iraqi Journal of Veterinary Sciences, 2021, Volume 35, Issue 3, Pages 437-442
DOI: 10.33899/ijvs.2020.126976.1424

The current study conducted to investigate the anatomical and histological structure of the cornea in sparrow hawk accipiter nisus. By using an optical microscope and histological stains. Anatomical results showed that the cornea composed of two parts, the peripheral cornea and the central cornea, and there was variation in corneal thickness according to the anatomical region. Histologically, the cornea consists of five layers. The first layer of the central cornea consists of non- keratinized stratified squamous epithelial tissue composed of four rows of cells. Whereas, Bowman's membrane appeared clear and thicker on the dorsal side than on the ventral side. The corneal stroma consists of collagen fibers arranged in three secondary layers within the stroma. The corneal stroma also distinguished by the presence of fibroblast cells, which randomly distributed among the collagen fibers. The Descemet membrane appeared clear and equal in thickness between the dorsal and ventral sides. The endothelium tissue appears in the form simple squamous epithelia. The histological structure of the cornea root seemed similar to its formation in the central cornea. Still, it characterized by the presence of pigment cells spread in the stromal corneal root. Among the distinct results that appeared in this study is the presence of blood vessels spreading in the root of the cornea. The study concluded that the anatomical and histological structure of the cornea in this bird distinguished by some specialties that contribute to increasing the effectiveness of the function of the cornea in this bird.